Dianabol (Metandienone)

April 3, 2022 by No Comments

Dianabol, also known as methandrostenolone (and / or methandienone/danabol), is an anabolic steroid commonly used by bodybuilders and athletes today. It became popular in the late 1960s and was widely used in the “golden age of bodybuilding” in the 1970s and 1980s. Methandrostenolone was developed in the mid-1960s by Dr. John Ziegler, representing the scientific community. This was claimed to be an American reaction to Soviet Olympian testosterone use. The drug, developed by the Ziegler team, was later introduced to Ciba under the Dianabol brand. It was the first synthetic oral anabolic steroid to be sold on the prescription drug market.

Dianabol (Metandienone)

Dianabol has a half-life of 4.5 to 6 hours. The drug has a moderate estrogenic effect and its rate of conversion to a metabolite with more pronounced androgenic properties of the enzyme 5-alpha-reductase is low. Due to the benefits of Dianabol, it has become popular among bodybuilders and athletes looking to increase muscle mass and strength.

The effect of Danabol on the athlete’s body

Dianabol has some limitations when it comes to C17 alpha-alkylation. As already mentioned, the methylation process activates the drug when taken orally and ensures its bioavailability, which does not destroy the anabolic steroid in the liver. However, the disadvantage of the modification is the increased hepatotoxicity of the drug. C17-alpha-alkylation increases the resistance of anabolic steroids to hepatic degradation, and all compounds with additional resistance to hepatic metabolism are more hepatotoxic. Therefore, the course duration for most users should be 4-6 weeks. This will maintain normal liver function and ensure organ recovery at the end of treatment. Liver enzymes often increase after taking Dianabol and then return to normal after stopping the medicine. Due to the risk of hepatotoxicity, methandrostenolone is commonly used as an excipient. Neither this drug nor other oral anabolic steroids should ever be used as monotherapy. It naturally inhibits testosterone and therefore leaves the body free of testosterone. Consumers should use a form of testosterone that is at least the same dose as THS (hormone replacement testosterone replacement).

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Methandrostenolone has moderate estrogenic activity and is flavored with an aromatase enzyme responsible for the conversion of androgens to estrogens. For this reason, Dianabol is known for estrogenic side effects such as fluid retention, the risk of gynecomastia, high blood pressure (mostly due to fluid retention), and a possible increase in fat accumulation. The drug has lower androgenic activity than testosterone, but the side effects and problems associated with it are still typical of Dianabol, although it is not as pronounced as testosterone. The risk assessment for androgenic side effects of methandrostenolone is 40-60, which is much lower than the corresponding testosterone score of 100, but the risk of side effects still exists, especially in individuals with individual sensitivities. These include an increased risk of baldness in men with a genetic predisposition, increased production of fat (oily skin) and the appearance of acne, and excessive hair growth on the face and body.

The effect of Danabol on the athlete's body

The effectiveness of Danabol is confirmed by the reviews of many weightlifters and in combination with other similar medicines it gives better results and prevents some side effects.

The benefits of using Danabol have a positive effect on relatively impressive weight training:

  • the active substances prevent the fluid from leaking out, thus eliminating the pain caused by the damage to the tissues;
  • the body recovers faster by increasing glycogen production and improving protein synthesis;
  • under the influence of the active components there is a rapid burning of fat;
  • as soon as possible is the external relief of the muscles;
  • significantly strengthens the skeletal system, ligaments and joints.
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Thus, Danabol has proven to be a very active medicine that helps to increase muscle mass, and if you follow it strictly, you can avoid side effects and potential addictions.

Drug properties

Since Dianabol has a very strong anabolic effect, its use to build muscle mass should not be in the high doses used in many other oral anabolic steroids. Methandrostenolone dosage should be considered with extreme caution considering the risk of hepatic side effects, as higher doses increase side effects.

It is important to note that the difference between beginner, intermediate and advanced is not the increased Dianabol dose. Many advanced bodybuilders get all the needed benefits at low doses.

Drug properties

Dianabol dosing regimen for women is not up for debate as this anabolic steroid variant is not very widely used in athletes due to the pronounced masculinizing effects.

Dianabol Side Effects

The most noticeable side effect of Dianabol is estrogen-related side effects, although studies have shown that the effect of Dianabol on the aromatase enzyme is moderate.

The most common side effects are bloating, fluid retention leading to an increase in blood pressure, gynecomastia (enlargement of the mammary glands) and acne (acne). These side effects can sometimes be reduced by antiestrogens such as the aromatase inhibitors Exemestane (Aromasin) and Arimidex, as well as the estrogen blocking medicines (SERMs) tamoxifen and Clomid.

In addition to estrogenic side effects, Dianabol can also cause androgenic effects (although less pronounced than testosterone). There is a risk of acne, oily skin, male pattern baldness and benign prostatic hyperplasia.

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Dianabol Side Effects

In addition to estrogenic side effects, Dianabol can also cause androgenic effects (although less pronounced than testosterone). There is a risk of acne, oily skin, male pattern baldness and benign prostatic hyperplasia.